Further, AUR with an annual risk of less than 1% is found to be uncommon, but requires urgent bladder catheterization. acute urinary retention (AUR) and the need for surgery either for AUR or deteriorating symptoms. It is a progressive disease and defined as worsening of symptoms, increase in prostate volume (PV), deterioration of urinary flow rate, inability to void i.e. ĭuring the last two decades, it has become clear that the management of LUTS associated with BPH is much more than just treating symptoms. androgen (dihydrotestosterone hypothesis) BPH occurs due to an age related changes in prostate androgen metabolism that favors the accumulation of DHT and responsible for cell growth in the tissues that lines the prostate gland thus rapid prostate enlargement. According to the most widely accepted hypothesis i.e. Though the etiology of hyerplastic process of BPH is clearly not known, but many partially overlapping and complementary theories have been proposed for the overgrowth of smooth muscle tissue and glandular epithelial tissue like aging: late activation of cell growth, defective cell death and hormonal changes.
īPH is also described as quality of life disorder, as its affects man’s ability to initiate or terminate urine flow stream (the symptoms interfere with the normal activities) and reduces the feeling of well being. Although urge incontinence is an irritative symptom, it may indicate the presence of obstruction.
Clinically BPH is manifested as lower urinary tract symptoms (LUTS) and consisting of voiding and storage symptoms such as slow urinary stream, splitting or spraying of urinary stream, recurrent urinary stream, straining to void and terminal dribbling, hesitancy, urgency, increased frequency, and incontinence.
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